Worldwide research trends on bronchiolitis in pediatrics.

BACKGROUND: The COVID-19 pandemic has led to a significant increase in cases of bronchiolitis among children. As a result, there has been a corresponding increase in the number of publications on this topic. It is essential to examine the main areas of focus within the scientific literature to understand the current trends in research on pediatric bronchiolitis. This research aims to analyze the types of scientific advances related to pediatric bronchiolitis, the research trends being pursued, and the countries and research institutions leading these efforts. By understanding these aspects of bronchiolitis research, we can better understand the current state of knowledge and identify areas where further research is needed. METHODS: To conduct a bibliometric analysis of the scientific literature on pediatric bronchiolitis, all relevant publications were retrieved from the Scopus database. The Scopus API and the SW VosViewer software with optimized modularity functions were used. This analysis was intended to provide a comprehensive overview of the current state of research on this topic, including the types of scientific advances being developed, the research trends being pursued, and the countries and research institutions leading these efforts. RESULTS: A total of 3810 publications were reviewed. We observed an increasing number of publications, particularly in recent years. Of these, 73.7% were articles, 95% were written in English, and 29.4% were from the United States. The main keywords used in these publications included: human, bronchiolitis, child, preschool, preschool child, major clinical study, controlled study, pneumonia, asthma, adolescent, hospitalization, infant, and newborn. These keywords were grouped into six clusters: outpatient management, long-term consequences, etiology, intensive care management, diagnostic methods, and the main cluster, which focused on hospital treatment and clinical studies. CONCLUSIONS: The bibliometric analysis of bronchiolitis research in pediatrics reveals that there has been a significant increase in the number of publications on this topic, particularly in recent years. Most of these publications are articles written in English and published in the United States. The main keywords used in these studies relate to various aspects of bronchiolitis, including diagnosis, treatment, and long-term consequences. The results of this analysis suggest that bronchiolitis is a topic of significant interest and concern for researchers and practitioners in the field of pediatrics and that further research is needed to improve our understanding and management of this condition.

Analysis of Fifty Years of Severe Malaria Worldwide Research.

This study analyzed fifty years of severe malaria research worldwide. Malaria is a parasitic disease that continues to have a significant impact on global health, particularly in sub-Saharan Africa. Severe malaria, a severe and often fatal form of the disease, is a major public health concern. The study used different bibliometric indicators such as the number of publications, citations, authorship, and keywords to analyze the research trends, patterns, and progress made in the field of severe malaria. The study covers the period from 1974 to 2021 and includes articles from Scopus. The results of the study indicated that there has been a steady increase in the number of publications on severe malaria over the past fifty years, with a particular increase in the last decade. The study also showed that most of the publications are from USA and Europe, while the disease occurs in Africa, South-East Asia, and the Americas. The study also identified the most frequent keywords used in the publications, and the most influential journals and authors in the field. In conclusion, this bibliometric study provides a comprehensive overview of the research trends and patterns in the field of severe malaria over the past fifty years and highlights the areas that need more attention and research efforts.

Precision Agriculture and Sensor Systems Applications in Colombia through 5G Networks.

The growing global demand for food and the environmental impact caused by agriculture have made this activity increasingly dependent on electronics, information technology, and telecommunications technologies. In Colombia, agriculture is of great importance not only as a commercial activity, but also as a source of food and employment. However, the concept of smart agriculture has not been widely applied in this country, resulting in the high production of various types of crops due to the planting of large areas of land, rather than optimization of the processes involved in the activity. Due to its technical characteristics and the radio spectrum considered in its deployment, 5G can be seen as one of the technologies that could generate the greatest benefits for the Colombian agricultural sector, especially in the most remote rural areas, which currently lack mobile network coverage. This article provides an overview of the current 5G technology landscape in Colombia and presents examples of possible 5G/IoT applications that could be developed in Colombian fields. The results show that 5G could facilitate the implementation of the smart farm in Colombia, improving current production and efficiency. It is useful when designing 5G implementation plans and strategies, since it categorizes crops by regions and products. This is based on budget availability, population density, and regional development plans, among others.

Transfer of parasitology research to patents worldwide.

Mankind has known about different parasitic diseases since ancient times. There is no doubt that parasites are the infectious agents that have caused the most deaths throughout history. But even today, parasitic diseases affect more than one billion people worldwide. In this paper, the relationship between articles published in the area of parasitology and international patents in this field from 1996 to 2019 was analyzed. For this purpose, Scopus has been used. This is a database developed by Elsevier, which, in addition to having numerous indexed journals and books, has developed SciVal, an analysis tool with which the publications that have been cited in the patents of the 5 largest patent offices in the world have been analyzed. The analysis has allowed us to study 2814 publications, to know their time trend, their Authors, Affiliations, and Countries, as well as the journals in which they have been published. Also, the topics and topic clusters related to parasitology that appear in publications cited in international patents have been known. Thus, the existence of six Topic Clusters that group 94% of all publications has been discovered. Of all of them, the Topic Cluster referring to malaria stands out above all others, with 968 articles (34% of the total), probably due to the fact that malaria continues to be, to this day, one of the great challenges for both industry and basic research throughout the world.

The Significance of Occupants' Interaction with Their Environment on Reducing Cooling Loads and Dermatological Distresses in East Mediterranean Climates.

Global endeavors to respond to the problems caused by climate change and are leading to higher temperatures inside homes, which can cause skin conditions (such as eczema), lethargy, and poor concentration; disturbed sleep and fatigue are also rising. The energy performance of buildings is influenced by interactions and associations of numerous different variables, such as the envelope specifications as well as the design, technologies, apparatuses, and occupant behaviours. This paper introduces simple and sustainable strategies that are not dependent on expensive or sophisticated technologies, as they rely only on the actions practiced by the building's occupants (movable window shading, and nighttime natural ventilation) instead of completely relying on high-cost mechanical cooling systems in buildings located in the main Eastern Mediterranean climates represented in the country of Jordan. These low-energy solutions could be applied to low-income houses in hot areas to avoid health problems, such as dermatological diseases, and save a significant amount of energy. The final results indicate that window shading has significant potential in reducing the cooling load in different climate zones. Natural ventilation exhibits high energy-saving abilities in climates that have cool nights, whereas its abilities in hot climates where nights are moderate is limited.

The Bibliometric Literature on Scopus and WoS: The Medicine and Environmental Sciences Categories as Case of Study.

In a broad sense, science can be understood as the knowledge contained in scientific manuscripts published in scientific journals. Scientific databases index only those journals that reach certain quality standards. Therefore, research and dissemination of scientific knowledge are essential activities for the growth of science itself. The aim of this manuscript is to assess the situation of medicine and environmental sciences among the bibliometric literature and to put it in perspective with the overall bibliometric publications in all scientific fields. The main countries publishing bibliometric manuscripts are China, USA and Spain. The latter country is ranked three out of the top five institutions according to the Scopus and WoS databases. In both databases, the average scientific collaboration of the top 20 institutions offers the same result, 41%. According to Scopus, the main subject categories in which this research falls are social sciences (38%), computer science (26%) and medicine (23%), while the environmental sciences category has 8%. In the analysis of the Medicine category alone, it has been observed that 136 countries have contributions in this field. The main countries are the United States, China and the United Kingdom. In the field of medicine, the main areas studied were: Epidemiology, Pediatrics, Orthopedics, Cardiology, Neurosurgery, Radiology, Ophthalmology, Oncology, Plastic Surgery and Psychiatry. With respect to environmental sciences, less international dissemination has been found, with only 83 countries having worked in this field. The main ones are China, Spain and the United States. Regarding the top 10 institutions, it can be stated that only Spain and China are relevant. Spain focuses on sustainability and China on the environment. The result of an independent keyword analysis of all published bibliometric manuscripts has shown that the main clusters are: Mapping Science (29%), Research Productivity (23%), Medicine (20%), Environmental Sciences (12%), Psychology (7%), Nursing (6%) and Engineering (4%). In short, medicine and environmental sciences are the most relevant areas in the field of bibliometrics after social sciences and computer sciences.

Bibliometric Studies and Worldwide Research Trends on Global Health.

Global health, conceived as a discipline, aims to train, research and respond to problems of a transboundary nature in order to improve health and health equity at the global level. The current worldwide situation is ruled by globalization, and therefore the concept of global health involves not only health-related issues but also those related to the environment and climate change. Therefore, in this Special Issue, the problems related to global health have been addressed from a bibliometric approach in four main areas: environmental issues, diseases, health, education and society.

The Contribution of Spanish Science to Patents: Medicine as Case of Study.

Investments in research and development (R&D) and innovation are expensive, and one wishes to be assured that there is positive feedback and to receive guidance on how to direct investments in the future. The social or economic benefits of investments in R&D are of particular interest to policymakers. In this regard, public expense in research, especially through universities, is sometimes being questioned. This paper establishes a measure of how research in Spain, and specifically in its universities, is involved. In this study, we have analyzed all the literature cited in the period 1998-2018 produced by Spanish institutions and which has been cited in at least one international patent, obtaining more than 40,000 publications from more than 160,000 different authors. The data have been surprisingly positive, showing that practically all public universities contribute to this subject and that there is a great deal of international collaboration, both in terms of the number of countries with which they collaborate and the prestige of the institutions involved. Regarding the specific scientific fields in which this collaboration is most relevant, biochemistry, genetics and molecular biology, and medicine together account for almost 40% of the total works. The topics most used by these publications were those of diseases or medical problems such as: Neoplams, Carcinoma, Alzheimer Disease, or human immunodeficiency virus (HIV-1). Oncology was according to the All Science Journal Classification (ASJC) the leading and central issue. Therefore, although the result of basic research is difficult to quantify, when it is observed that there is a return in fields such as medicine or global health, it can be said that it is well employed. In terms of journals from a purely bibliometric point of view, it has been observed that some journals do not have a great impact or relative position within their categories, but they do have a great relevance in this area of patent support. Therefore, it would be worthwhile to set up a rank for scientific journals based on the citations of patents, so the percentage of articles cited in patents with Field-Weighted Citation Impact (FWCI) >1, and as an indicator of scientific transfer from universities or research centres, the transference index in patents (TIP) is also proposed.

Worldwide Research Trends on Medicinal Plants.

The use of medicinal plants has been done since ancient times and may even be considered the origin of modern medicine. Compounds of plant origin have been and still are an important source of compounds for drugs. In this study a bibliometric study of all the works indexed in the Scopus database until 2019 has been carried out, analyzing more than 100,000 publications. On the one hand, the main countries, institutions and authors researching this topic have been identified, as well as their evolution over time. On the other hand, the links between the authors, the countries and the topics under research have been analyzed through the detection of communities. The last two periods, from 2009 to 2014 and from 2015 to 2019, have been examined in terms of research topics. It has been observed that the areas of study or clusters have been reduced, those of the last period being those engaged in unclassified drug, traditional medicine, cancer, in vivo study-antidiabetic activity, and animals-anti-inflammatory activity. In summary, it has been observed that the trend in global research is focused more on the search for new medicines or active compounds rather than on the cultivation or domestication of plant species with this demonstrated potential.

Wastewater Treatment by Advanced Oxidation Process and Their Worldwide Research Trends.

Background: Water is a scarce resource and is considered a fundamental pillar of sustainable development. The modern development of society requires more and more drinking water. For this cleaner wastewater, treatments are key factors. Among those that exist, advanced oxidation processes are being researched as one of the sustainable solutions. The main objective of this manuscript is to show the scientific advances in this field. Methods: In this paper, a systematic analysis of all the existing scientific works was carried out to verify the evolution of this line of research. Results: It was observed that the three main countries researching this field are China, Spain, and the USA. Regarding the scientific collaboration between countries, three clusters were detected-one of Spain, one of China and the USA, and one of Italy and France. The publications are grouped around three types of water: industrial, urban, and drinking. Regarding the research, 15 clusters identified from the keywords analyzed the advanced oxidation process (alone or combined with biological oxidation) with the type of wastewater and the target pollutant, removal of which is intended. Finally, the most important scientific communities or clusters detected in terms of the number of published articles were those related to the elimination of pollutants of biological origin, such as bacteria, and of industrial nature, such as pesticides or pharmaceutical products.

The state of global research on social work and disability.

Two paradigms are used to define disability. On the one hand, the biological paradigm, which attends to a person's deficiencies and difficulties. And, on the other hand, the social, which does not treat disability as a pathology, but rather places the focus of interest on the deficient tools that society has to consider the capabilities of everyone. This article analyzes the scientific production on disability and social work, using bibliometric techniques and algorithms for the detection of communities, taking into account the current state of research worldwide. This analysis offers a holistic view of the characteristics of the work carried out in the world on this subject.

Analysis of Global Research on Malaria and Plasmodium vivax.

Background: Malaria is one of the infectious diseases of greatest interest to the scientific community and of greatest concern to international health authorities. Traditionally, the focus has been on Plasmodium falciparum, the parasite that causes the most severe form of the disease in Africa. However, in the last twenty years, the Plasmodium vivax parasite, responsible for a large number of cases in Latin America, the Middle East, South and Southeast Asia, the Horn of Africa, and Oceania, has also generated enormous interest due, among other things, to the published evidence that it can cause severe malaria. Methods: In this paper, the international scientific publication on malaria and P. vivax has been analyzed using the Scopus database to try to define global trends in this field of study. Results: It has been shown that events such as the emergence of resistance to certain drugs can break a trend. The important role of non-malaria-endemic countries such as the USA or Switzerland in malaria research is also evident. Conclusions: International cooperation will be essential for the eradication of the disease. Moreover, in this sense, the general vision given by the bibliometric analysis of malaria caused by P. vivax is fundamental to paint the picture regarding the current situation and encourage international cooperation and control efforts.

An Open Hardware Design for Internet of Things Power Quality and Energy Saving Solutions.

An important challenge for our society is the transformation of traditional power systems to a decentralized model based on renewable energy sources. In this new scenario, advanced devices are needed for real-time monitoring and control of the energy flow and power quality (PQ). Ideally, the data collected by Internet of Thing (IoT) sensors should be shared to central cloud systems for online and off-line analysis. In this paper openZmeter (oZm) is presented as an advanced low-cost and open-source hardware device for high-precision energy and power quality measurement in low-voltage power systems. An analog front end (AFE) stage is designed and developed for the acquisition, conditioning, and processing of power signals. This AFE can be stacked on available quadcore embedded ARM boards. The proposed hardware is capable of adapting voltage signals up to 800 V AC/DC and currents up to thousands of amperes using different probes. The oZm device is described as a fully autonomous open-source system for the computation and visualization of PQ events and consumed/generated energy, along with full details of its hardware implementation. It also has the ability to send data to central cloud management systems. Given the small size of the hardware design and considering that it allows measurements under a wide range of operating conditions, oZm can be used both as bulk metering or as metering/submetering device for individual appliances. The design is released as open hardware and therefore is presented to the community as a powerful tool for general usage.

Plasmodium genomics: an approach for learning about and ending human malaria.

Malaria causes high levels of morbidity and mortality in human beings worldwide. According to the World Health Organization (WHO), about half a million people die of this disease each year. Malaria is caused by six species of parasites belonging to the Plasmodium genus: P. falciparum, P. knowlesi, P. vivax, P. malariae, P. ovale curtisi, and P. ovale wallikeri. Currently, malaria is being kept under control with varying levels of elimination success in different countries. The development of new molecular tools as well as the use of next-generation sequencing (NGS) technologies and novel bioinformatic approaches has improved our knowledge of malarial epidemiology, diagnosis, treatment, vaccine development, and surveillance strategies. In this work, the genetics and genomics of human malarias have been analyzed. Since the first P. falciparum genome was sequenced in 2002, various population-level genetic and genomic surveys, together with transcriptomic and proteomic studies, have shown the importance of molecular approaches in supporting malaria elimination.

The Identification of Scientific Communities and Their Approach to Worldwide Malaria Research.

It is essential to establish a pattern to detect the strengths and weaknesses of working groups publishing on malaria, to promote coordination to facilitate the eradication of the disease. Given the complexity of the scientific network of groups and institutions studying malaria, it is necessary to use a mathematical algorithm that allows us to know the real structure of research on the disease in the world. In this work, articles with the word "malaria" in the title or author keywords gathered from Elsevier Scopus database were analyzed. By means of specific software, graphs were created. The analysis of the data allowed established different scientific communities, among which two were very diverse: one formed by those groups concerned about the vector transmission and control, and another one focused on the drug resistance of the parasite. Basic, applied, and operational research to eradicate malaria is an ambitious goal of the international institutions and the scientific community. The combination of effort and the establishment of a worldwide-scientific network that allows an effective interconnection (exchange) of knowledge, infrastructure technology, collaborators, financial resources, and datasets will contribute more effectively to end the disease.

Global trends in nitrate leaching research in the 1960-2017 period.

Nitrate leaching is the process whereby the nitrate (NO3-) anion moves downwards in the soil profile with soil water. Nitrate leaching is commonly associated with chemical nitrogen (N) fertilizers used in agriculture. Nitrate leaching from different sources and contamination of surface and groundwater is a global phenomenon that has prompted social and political pressure to reduce nitrate leaching and contamination of water bodies. This bibliometric study analyzed global trends in nitrate leaching research. The results showed a rising interest in the last decades in this topic; given the growth tendency over the last years, it was envisaged that the importance on nitrate leaching research will continue increasing in the future. Knowledge on nitrate leaching was mostly disseminated through scientific publications (90% of total documents recovered), both as journal articles and reviews, classified in the Scopus database in the Agricultural, Biological and Environmental Sciences areas. Most publications dealt with soil nitrogen losses from agroecosystems and farmlands and the associated impact on the environment; they were published in journals with a focus on the influence of anthropogenic and soil-crop-animal systems in the environment, and on how such changes in the environment impact agroecosystems. Most documents published on nitrate leaching were indisputably from the United States, followed by China, the United Kingdom and Germany. An analysis of the main keywords showed an overall dominance of the soil nitrogen cycle, fertilizer use in agriculture and water quality aspects. The evolution of main crop species involved in nitrate leaching research showed a rising relevance of research conducted with maize, wheat and grasses from 1990 onwards. The most productive institutions in terms of number of documents dealing with nitrate leaching research, h-index and total citations, were located in the United States, China and the Netherlands. The United States Department of Agriculture stood out, followed by the Chinese Academy of Sciences and Wageningen University and Research. There were clusters of institutions with intercontinental interaction, on nitrate leaching research, between institutions from Europe, Asia and South and North America. Overall, this study has highlighted, from a bibliometric perspective, the rising concern on nitrate leaching. Progress in this field has been made particularly on the impact of the soil-plant-animal system on the environment and agroecosystems, and on fundamental and applied aspects of plant-soil interactions with an emphasis in cropping systems.

Genetic approach towards a vaccine against malaria.

Malaria is a major concern for international health authorities. Millions of people contract it every year in the world due to a parasite of the Plasmodium genus. Due to the complexity of the parasite biology and genetics, there is currently no vaccine against the disease. However, due to the great resistance both to the medicines and to the insecticides used to combat the disease, it has become essential to obtain a vaccine as the necessary tool to prevent transmission and eliminate the disease. The bibliometric data indicate that interest in vaccines has been growing steadily since the 1980s. But nowadays, a powerful tool is used: the Plasmodium genome. This allows us to improve the fight against the disease. Knowing the sequences of the genes that favor the appearance of drug resistance, or those that encode for proteins with greater antigenic response, is a tool that can become fundamental. This article reviews the state of the art on vaccines and genetics, in the fight against malaria, and analyzes the fixed photo that the worldwide research on the disease poses.

Human parasitology worldwide research.

In this article, the trends in human parasitology have been studied through the analysis of the number of publications in this area. The parameters studied were: number of articles, language, countries and institutions with the highest number of publications, and keywords with greater presence in the articles of human parasitology. The results of the analysis confirm the growing interest in this area, observing an exponential growth in the number of publications in the last decades. We also verified that the main country in terms of scientific production is the USA, although among the most important institutions, we find non-US centres such as the Oswaldo Cruz Foundation and the London School of Hygiene and Tropical Medicine. For observing the relative importance of the journals that publish articles in this specific topic, an index has been created based on the h-index of the journal with publications related to human parasitology and divided by every 100 items. This rank is led fist by 'Journal of Medical Entomology' closely followed by 'Parasitology'. The analysis of the keywords allows to draw conclusions about the great importance of malaria in the current world research. A change in analytical methodology is also observed, and molecular techniques are now being imposed. These techniques, in the near future, have to influence in an improvement in the treatments and prevention of the diseases caused by parasites. Finally, it can be seen that diseases traditionally studied as helminthiasis and amebiasis are currently as well studied as others such as toxoplasmosis or leishmaniasis.

Trends in plant research using molecular markers.

MAIN CONCLUSION: A deep bibliometric analysis has been carried out, obtaining valuable parameters that facilitate the understanding around the research in plant using molecular markers. The evolution of the improvement in the field of agronomy is fundamental for its adaptation to the new exigencies that the current world context raises. In addition, within these improvements, this article focuses on those related to the biotechnology sector. More specifically, the use of DNA markers that allow the researcher to know the set of genes associated with a particular quantitative trait or QTL. The use of molecular markers is widely extended, including: restriction fragment length polymorphism, random-amplified polymorphic DNA, amplified fragment length polymorphism, microsatellites, and single-nucleotide polymorphisms. In addition to classical methodology, new approaches based on the next generation sequencing are proving to be fundamental. In this article, a historical review of the molecular markers traditionally used in plants, since its birth and how the new molecular tools facilitate the work of plant breeders is carried out. The evolution of the most studied cultures from the point of view of molecular markers is also reviewed and other parameters whose prior knowledge can facilitate the approach of researchers to this field of research are analyzed. The bibliometric analysis of molecular markers in plants shows that top five countries in this research are: US, China, India, France, and Germany, and from 2013, this research is led by China. On the other hand, the basic research using Arabidopsis is deeper in France and Germany, while other countries focused its efforts in their main crops as the US for wheat or maize, while China and India for wheat and rice.

DNA Damage Repair System in Plants: A Worldwide Research Update.

Living organisms are usually exposed to various DNA damaging agents so the mechanisms to detect and repair diverse DNA lesions have developed in all organisms with the result of maintaining genome integrity. Defects in DNA repair machinery contribute to cancer, certain diseases, and aging. Therefore, conserving the genomic sequence in organisms is key for the perpetuation of life. The machinery of DNA damage repair (DDR) in prokaryotes and eukaryotes is similar. Plants also share mechanisms for DNA repair with animals, although they differ in other important details. Plants have, surprisingly, been less investigated than other living organisms in this context, despite the fact that numerous lethal mutations in animals are viable in plants. In this manuscript, a worldwide bibliometric analysis of DDR systems and DDR research in plants was made. A comparison between both subjects was accomplished. The bibliometric analyses prove that the first study about DDR systems in plants (1987) was published thirteen years later than that for other living organisms (1975). Despite the increase in the number of papers about DDR mechanisms in plants in recent decades, nowadays the number of articles published each year about DDR systems in plants only represents 10% of the total number of articles about DDR. The DDR research field was done by 74 countries while the number of countries involved in the DDR & Plant field is 44. This indicates the great influence that DDR research in the plant field currently has, worldwide. As expected, the percentage of studies published about DDR systems in plants has increased in the subject area of agricultural and biological sciences and has diminished in medicine with respect to DDR studies in other living organisms. In short, bibliometric results highlight the current interest in DDR research in plants among DDR studies and can open new perspectives in the research field of DNA damage repair.